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MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943; Oxford University Press; Volume: 28; Issue: 6 Linguagem: Inglês

10.1093/genetics/28.6.491

1943-2631

S. E. Luria, M. Delbrück,

Evolution and Genetic Dynamics

This article reported Luria and Delbruck's breakthrough study in which they established that viruses do not induce mutations in bacteria, but that virus-resisting mutations are spontaneous. Their fluctuation test theory demonstrated that bacteria were ideal subjects for genetic research.