WEARABLE ARTIFICIAL ENDOCRINE PANCREAS WITH NEEDLE-TYPE GLUCOSE SENSOR
1982; Elsevier BV; Volume: 320; Issue: 8308 Linguagem: Inglês
10.1016/s0140-6736(82)92788-x
ISSN1474-547X
AutoresMotoaki Shichiri, Yoshimitsu Yamasaki, Ryuzo Kawamori, Nobuyoshi Hakui, Hiroshi Abe,
Tópico(s)Hyperglycemia and glycemic control in critically ill and hospitalized patients
ResumoMiniaturisation of the bedside artificial endocrine pancreas is necessary to provide a means of restoring physiological glycaemic excursions in diabetic patients in the long term. One of the remaining problems in producing such a sophisticated device is the difficulty in developing a sufficiently small glucose-monitoring system. A needle-type glucose sensor has been developed which is suitable for use in a closed-loop glycaemic control system. The wearable artificial endocrine pancreas, incorporating the needle-type glucose sensor, a computer calculating infusion rates of insulin, glucagon, or both, and infusion pumps, was tested in pancreatectomised dogs: the device produced perfect control of blood glucose for up to 7 days.
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