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Are prenyl groups on proteins sticky fingers or greasy handles?

2003; Portland Press; Volume: 376; Issue: 1 Linguagem: Inglês

10.1042/bj20031531

1470-8728

Anthony I. Magee, Miguel C. Seabra,

Glycosylation and Glycoproteins Research

This Commentary discusses the work of Dietrich et al. in this issue of the Biochemical Journal, which sheds new light on the biological roles of protein-bound prenyl groups by providing evidence that the α-subunit of the heterotrimeric G-protein transducin has a binding site for the geranylgeranyl group of the γ-subunit.