Artigo Acesso aberto Revisado por pares

Cellware—a multi-algorithmic software for computational systems biology

2004; Oxford University Press; Volume: 20; Issue: 8 Linguagem: Inglês

10.1093/bioinformatics/bth067

ISSN

1367-4811

Autores

Pawan K. Dhar, Tan Chee Meng, Sandeep Somani, Ye Li, Anand Sairam, Mandar Chitre, Hao Zhu, Kishore R. Sakharkar,

Tópico(s)

Bioinformatics and Genomic Networks

Resumo

Abstract Summary: The intracellular environment of a cell hosts a wide variety of enzymatic reactions, diffusion events, molecular binding, polymerization and metabolic channeling. To transform these biological events into a computational framework, distinct modeling strategies are required. While currently no tool is capable of capturing all these events, progress is being made to create an integrated environment for the modeling community. To address this niche requirement, Cellware has been developed to offer a multi-algorithmic environment for modeling and simulating both deterministic and stochastic events in the cell. Availability: The software is available for free and can be downloaded from http://www.bii.a-star.edu.sg/sbg/cellware

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