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Poor Potential Coverage for 7-Valent Pneumococcal Conjugate Vaccine, Malawi

2003; Centers for Disease Control and Prevention; Volume: 9; Issue: 6 Linguagem: Inglês

10.3201/eid0906.030020

1080-6059

Stephen B. Gordon, Stonard Kanyanda, Amanda L. Walsh, Kirsty Goddard, Mas Chaponda, Victoria Atkinson, Wakisa Mulwafu, Elizabeth Molyneux, Ed E. Zijlstra, Malcolm E. Molyneux, Stephen M. Graham,

Respiratory viral infections research

Abstract Streptococcus pneumoniae infections can be prevented by using new conjugate vaccines, but these vaccines have limited serogroup coverage. We report the first serogrouping data from carried and invasive isolates obtained from children and adults in Malawi. The 7-valent vaccine would cover 41% of invasive isolates from children and 25% from adults. A 9-valent vaccine, including types 1 and 5, would cover 66% of invasive isolates from children and 55% from adults.