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BIBTEX RIS

New Model of Oropharyngeal Candidiasis in Mice

2001; American Society for Microbiology; Volume: 45; Issue: 11 Linguagem: Inglês

10.1128/aac.45.11.3195-3197.2001

ISSN

1098-6596

Autores

Yasuki Kamai, Mikie Kubota, Yoko Kamai, Tsunemichi Hosokawa, Takashi Fukuoka, Scott G. Filler,

Tópico(s)

Fungal Infections and Studies

Resumo

We established a straightforward murine model of oropharyngeal candidiasis. Mice were immunosuppressed with cortisone acetate, anesthetized, and then inoculated by placing cotton wool balls saturated with Candida albicans sublingually for 2 h. A prolonged, reproducible infection was induced. This model may be useful for antifungal screening or pathogenesis studies.

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