SACS—Self-maintaining database of antibody crystal structure information
2002; Oxford University Press; Volume: 18; Issue: 1 Linguagem: Inglês
10.1093/bioinformatics/18.1.175
ISSN1367-4811
AutoresLee C. Allcorn, Andrew C.R. Martin,
Tópico(s)Protein purification and stability
ResumoAbstract Motivation: The rapid increase in the number of structures in the Protein Databank (PDB) makes it difficult to find all structures in a given protein class. Automatically-maintained web-based summaries are one solution to this problem. Results: Summary of Antibody Crystal Structures (SACS), a self-maintaining web-site containing summary information on antibody structures in the PDB, is described. Mirrored PDB data are processed automatically using a Make-based system to identify new antibody structures. The PDB header records and sequence data are then parsed to identify a number of features of the structure and the data are stored using eXtensible Markup Language (XML). eXtensible Stylesheet Language: Transformations (XSLT), a new style sheet language for XML, is used to generate Hypertext Markup Language (HTML) pages containing either a one-line summary of every structure or a more detailed page describing a single antibody. Availability: The pages are accessible at http://www.bioinf.org.uk/abs/sacs/or http://www.rubic.rdg.ac.uk/abs/sacs/ Contact: a.c.r.martin@reading.ac.uk; andrew@bioinf.org.uk * To whom correspondence should be addressed.
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