Artigo Acesso aberto Revisado por pares

Impact of Young Age on Treatment Efficacy and Safety in Advanced Colorectal Cancer: A Pooled Analysis of Patients From Nine First-Line Phase III Chemotherapy Trials

2011; Lippincott Williams & Wilkins; Volume: 29; Issue: 20 Linguagem: Inglês

10.1200/jco.2010.33.5281

ISSN

1527-7755

Autores

Charles D. Blanke, Brian M. Bot, David M. Thomas, Archie Bleyer, Claus-Henning Köhne, Michel Seymour, Aimery de Gramont, Richard M. Goldberg, Daniel J. Sargent,

Tópico(s)

Colorectal Cancer Surgical Treatments

Resumo

Colorectal cancer predominantly occurs in the elderly, but approximately 5% of patients are 50 years old or younger. We sought to determine whether young age is prognostic, or whether it influences efficacy/toxicity of chemotherapy, in patients with advanced disease.

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