Portal de Periódicos da CAPES

NetPath: a public resource of curated signal transduction pathways

2010; BioMed Central; Volume: 11; Issue: 1 Linguagem: Inglês

10.1186/gb-2010-11-1-r3

1474-760X

Kumaran Kandasamy, S Sujatha Mohan, Rajesh Raju, Shivakumar Keerthikumar, Ghantasala S. Sameer Kumar, Abhilash K Venugopal, Deepthi Telikicherla, J. Daniel Navarro, Suresh Mathivanan, C. Pecquet, Sashi Kanth Gollapudi, Sudhir Gopal Tattikota, Shyam Mohan, Hariprasad Padhukasahasram, Yashwanth Subbannayya, Renu Goel, Harrys K.C. Jacob, Jun Zhong, Raja Sekhar Nirujogi, Vishalakshi Nanjappa, Lavanya Balakrishnan, Roopashree Subbaiah, YL Ramachandra, B. A. Rahiman, Thottethodi Subrahmanya Keshava Prasad, Jian-Xin Lin, Jon C. D. Houtman, Stephen Desiderio, Jean‐Christophe Renauld, Stefan N. Constantinescu, Osamu Ohara, Toshio Hirano, Masato Kubo, Sujay Singh, Purvesh Khatri, Sorin Drăghici, Gary D. Bader, Chris Sander, Warren J. Leonard, Akhilesh Pandey,

Biomedical Text Mining and Ontologies

Abstract We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.