2‐Methylthio‐7‐desazainosin und sein α‐Anomer — Debenzylierung von Thionucleosiden mit Bortrichlorid
1982; Wiley; Volume: 1982; Issue: 4 Linguagem: Inglês
10.1002/jlac.198219820422
ISSN0170-2041
Autores Tópico(s)Polyamine Metabolism and Applications
Resumo2‐Methylthio‐7‐deazainosine and its α‐Anomer — Debenzylation of Thionucleosides with Boron Trichloride Debenzylation of the sugar moiety of pyrrolo[2,3‐ d ]pyrimidine nucleosides without affecting methoxy or methylthio substituents of the chromophore has been accomplished by the action of boron trichloride/dichloromethane at — 78°C. Applying this method to the protected derivatives 1b or 2b the methylthio nucleosides 3 and 4 were obtained in high yields.
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