Produção Nacional
Revisado por pares
Kaempferitrin from Uncaria guianensis (Rubiaceae) and its potential as a chemical marker for the species
2009; Brazilian Chemical Society; Volume: 20; Issue: 6 Linguagem: Inglês
10.1590/s0103-50532009000600007
ISSN1678-4790
AutoresLígia M. M. Valente, Carlos Henrique Brasil Bizarri, Sally Liechocki, Rodolfo S. Barboza, Djavan da Paixão, Maria Beatriz Almeida, Paulo José Coelho Benevides, Alviclér Magalhães, Antônio Carlos Siani,
Tópico(s)Traditional and Medicinal Uses of Annonaceae
ResumoUncaria tomentosa (Willd.) DC. and U. guianensis (Aubl.) Gmel., known as cat's claw, are large woody vines native to the Amazonian and Central American rainforests. The species contain, in different proportions, indole and oxindole alkaloids, triterpenoid glycosides, sterols and proanthocyanidins. U. tomentosa can be chemically identified by its oxindole alkaloid profile and content, whereas U. guianensis has no satisfactorily established chemical markers. This work describes, for the first time, the isolation of kaempferol-3,7-O-(α)-dirhamnoside (kaempferitrin) in Uncaria species. Screening for this compound in leaves, stems or bark of both species through TLC and HPLC-DAD-MS showed the presence of kaempferitrin only in the leaves and stems of U. guianensis, at a ratio almost thirty six times greater in the leaves than in the stems. These results reveal the selectivity of U. guianensis to produce this bioactive flavonoid glycoside, and suggest this compound as a potential chemical marker for the species.
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