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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Micafungin Enhances Neutrophil Fungicidal Functions against Candida Pseudohyphae

2004; American Society for Microbiology; Volume: 48; Issue: 7 Linguagem: Inglês

10.1128/aac.48.7.2730-2732.2004

ISSN

1098-6596

Autores

Cristina Gil‐Lamaignere, Stefanie Salvenmoser, Regina Hess, Frank‐Michael C. Müller,

Tópico(s)

Fungal Infections and Studies

Resumo

We evaluated the effect of the combination of micafungin and polymorphonuclear leukocytes (PMN) against hyphae of Candida albicans and Candida dubliniensis. Micafungin enhanced the PMN oxidative burst dose dependently. The combination was synergistic (C. albicans) or additive (C. dubliniensis); when PMN were pretreated with granulocyte-macrophage colony-stimulating factor, the combination was more effective.

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