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Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa

2015; American Association for the Advancement of Science; Volume: 350; Issue: 6262 Linguagem: Inglês

10.1126/science.aad2879

1095-9203

Marcos Gallego Llorente, Eppie R. Jones, Anders Eriksson, Veronika Siska, Kathryn Weedman Arthur, John Arthur, Matthew C. Curtis, Jay T. Stock, Mauro Coltorti, Pierluigi Pieruccini, Sean Stretton, Fiona Brock, Thomas Higham, Y. Park, Michael Hofreiter, Daniel G. Bradley, Jong Bhak, Ron Pinhasi, Andrea Manica,

Eurasian Exchange Networks

Characterizing genetic diversity in Africa is a crucial step for most analyses reconstructing the evolutionary history of anatomically modern humans. However, historic migrations from Eurasia into Africa have affected many contemporary populations, confounding inferences. Here, we present a 12.5× coverage ancient genome of an Ethiopian male ("Mota") who lived approximately 4500 years ago. We use this genome to demonstrate that the Eurasian backflow into Africa came from a population closely related to Early Neolithic farmers, who had colonized Europe 4000 years earlier. The extent of this backflow was much greater than previously reported, reaching all the way to Central, West, and Southern Africa, affecting even populations such as Yoruba and Mbuti, previously thought to be relatively unadmixed, who harbor 6 to 7% Eurasian ancestry.