Emerging Eosinophilic (Allergic) Esophagitis: Increased Incidence or Increased Recognition?
2007; American Medical Association; Volume: 131; Issue: 5 Linguagem: Inglês
10.1043/1543-2165(2007)131[777
ISSN1543-2165
AutoresAndrew D. Vanderheyden, Robert E. Petras, Barry R. DeYoung, Frank A. Mitros,
Tópico(s)Eosinophilic Disorders and Syndromes
ResumoAbstract Context.—Eosinophilic esophagitis is a disease of the esophagus with distinct histologic features (prominent intraepithelial eosinophils, particularly superficial with clustering) and characteristic endoscopic features (trachealization, white plaques). The presence of intraepithelial eosinophils had been recognized since 1982 as indicative of reflux esophagitis but little attention was initially paid to their numbers or location. Eosinophilic esophagitis has been recently described and there have been a number of reports that its incidence is on the rise. It had been our impression that eosinophilic esophagitis was being seen more frequently, perhaps resulting from some environmental change. Objective.—To investigate the increased prevalence of eosinophilic esophagitis. Design.—We analyzed a similar group of cases from 2005 (n = 150) as compared with 1990 (n = 115). Consecutive patients with mucosal esophageal biopsies from May through June of the respective years were included in the analysis. P...
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