A modified procedure for the Dakin–West reaction: an efficient and convenient method for a one-pot synthesis of β-acetamido ketones using silica sulfuric acid as catalyst
2005; Elsevier BV; Volume: 46; Issue: 12 Linguagem: Inglês
10.1016/j.tetlet.2005.01.149
ISSN1873-3581
AutoresMohammd M. Khodaei, Ahmad Reza Khosropour, Peyman Fattahpour,
Tópico(s)Synthesis of heterocyclic compounds
ResumoA one-pot, four-component condensation of an aryl aldehyde, an aryl ketone, acetyl chloride and acetonitrile in the presence of silica sulfuric acid as an active, inexpensive, recoverable and recyclable catalyst is disclosed for the synthesis of β-acetamido ketones.
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