Relationship of human plasma leptin concentration with blood cell parameters.
2000; Centre National de la Recherche Scientifique; Volume: 85; Issue: 9 Linguagem: Inglês
Autores
Patrick Laharrague, J Corberand, Luc Pénicaud, Louis Casteilla,
Tópico(s)Dietary Effects on Health
ResumoNo strong relationship between leptin and hematologic values was found in a large series of European patients and control subjects. However a role for high levels of leptin in situations such as obesity or sepsis cannot be excluded, as suggested by the weak correlation between leptin and leukocyte count observed in hospitalized patients. Sir, Leptin is expressed by adipocytes and involved in the regulation of body weight and body fat. The characterization of a leptin receptor on CD34 + cells 1-3 and a proliferative effect of leptin on hematopoietic cells in culture 1,2,4,5 suggest a relationship between leptin
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