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Microelectrode Recording of Ion Activity in Brain

1974; Springer Nature; Linguagem: Inglês

10.1007/978-1-4615-9023-1_11

2214-8019

Thomas Zeuthen, R. C. Hiam, Ian A. Silver,

Advanced Chemical Sensor Technologies

This paper deals with some technical aspects of the registration of extracellular potassium (K+) activity in the cortex of rats during hypoxia either by means of single-barrelled microelectrodes utilizing K+-sensitive liquid ion-exchanger (Corning Catalog no. 477317) (Cornwall et al., 1970; Khuri, 1971; Walker, 1971, 1973) or by means of double-barrelled microelectrodes, where one barrel measures electrical potential (the DC-barrel) and the other barrel measures electrical potential plus a potential determined by the K+-activity. (Vyskocil et al., 1972). We used a different method of producing double-barrelled electrodes from that described by Khuri et al., (1972a; 1972b) in order to obtain long shanks (5–10mm).