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Monocyte Diversity in Myocardial Infarction

2009; Elsevier BV; Volume: 54; Issue: 2 Linguagem: Inglês

10.1016/j.jacc.2009.03.047

1558-3597

Eduard Shantsila, Gregory Y.H. Lip,

Chemokine receptors and signaling

A key role for monocyte-derived macrophages for the development, progression, and destabilization of atherosclerotic plaques has long been recognized. However, the scale of relatively focal macrophage activity in the plaque changes dramatically after atherothrombotic complications. While local