Voltar
Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

CHEMICAL STUDY AND ANTIPROLIFERATIVE, TRYPANOCIDAL AND LEISHMANICIDAL ACTIVITIES OF Maxillaria picta

2014; Brazilian Chemical Society; Linguagem: Inglês

10.5935/0100-4042.20140179

ISSN

1678-7064

Autores

Thiago L. de Almeida, Josiane A. Monteiro, Greice K.P. Lopes, Lucas Ulisses Rovigatti Chiavelli, Silvana Maria de Oliveira Santin, Cleuza C. da Silva, Vanessa Kaplum, Débora B. Scariot, Celso Vataru Nakamura, Ana Lúcia Tasca Góis Ruiz, João Ernesto de Carvalho, Ricardo Tadeu de Faria, Armando M. Pomini,

Tópico(s)

Research on Leishmaniasis Studies

Resumo

Maxillaria picta.The chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoyunbene C, in addition to four phenolic acids, one xanthone, steroidal compounds and two triterpenes.Crude extract, fractions, subfractions and the isolated xanthone were evaluated for anticancer activity against human tumor cell lines and against evolutionary forms of T. cruzi and L. amazonensis.The structures of the compounds were determined by GC-MS, and 1 H NMR, 13 C NMR spectral methods as well as bidimensional techniques.

Referência(s)