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English language version of the S3-consensus guidelines on chronic pancreatitis: Definition, aetiology, diagnostic examinations, medical, endoscopic and surgical management of chronic pancreatitis

2015; Thieme Medical Publishers (Germany); Volume: 53; Issue: 12 Linguagem: Inglês

10.1055/s-0041-107379

1439-7803

Albrecht Hoffmeister, Julia Mayerle, Christoph Beglinger, M.W. Büchler, Philip Bufler, Katarina Dathe, U.R. Fölsch, Helmut Frieß, Jakob R. Izbicki, Stefan Kahl, E. Klar, Jutta Keller, Wolfram Trudo Knoefel, Peter Layer, Matthias Loehr, Rémy Meier, J. F. Riemann, Michael Rünzi, Roland M. Schmid, A. Schreyer, Barbara Tribl, Jens Werner, Heiko Witt, Joachim Mössner, Markus M. Lerch,

Gastrointestinal disorders and treatments

Chronic pancreatitis is a disease of the pancreas in which recurrent inflammatory episodes result in replacement of pancreatic parenchyma by fibrous connective tissue. This fibrotic reorganisation of the pancreas leads to a progressive exocrine and endocrine pancreatic insufficiency. In addition, characteristic complications arise, such as pseudocysts, pancreatic duct obstructions, duodenal obstruction, vascular complications, obstruction of the bile ducts, malnutrition and pain syndrome. Pain presents as the main symptom of patients with chronic pancreatitis. Chronic pancreatitis is a risk factor for pancreatic carcinoma. Chronic pancreatitis significantly reduces the quality of life and the life expectancy of affected patients. These guidelines were researched and compiled by 74 representatives from 11 learned societies and their intention is to serve evidence-based professional training as well as continuing education. On this basis they shall improve the medical care of affected patients in both the inpatient and outpatient sector. Chronic pancreatitis requires an adequate diagnostic workup and systematic management, given its severity, frequency, chronicity, and negative impact on the quality of life and life expectancy.