Portal de Periódicos da CAPES

Reversibility of Detrusor Hypertrophy and Hyperplasia After Removal of Infravesical Outflow Obstruction in the Rat

1988; Lippincott Williams & Wilkins; Volume: 140; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(17)41746-0

1527-3792

Per Lindnér, Anders Mattiasson, Lo Persson, Bengt Uvelius,

Stress Responses and Cortisol

No AccessJournal of Urology1 Sep 1988Reversibility of Detrusor Hypertrophy and Hyperplasia After Removal of Infravesical Outflow Obstruction in the Rat P. Lindnér, A. Mattiasson, L. Persson, and B. Uvelius P. LindnérP. Lindnér , A. MattiassonA. Mattiasson , L. PerssonL. Persson , and B. UveliusB. Uvelius View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)41746-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The present investigation was performed in order to study the degree of reversibility of changes of the rat detrusor secondary to infravesical outflow obstruction for various periods of time. In a previous study it was shown that outflow obstruction induced both hypertrophy and hyperplasia of the smooth muscle cells. This was determined by means of morphometry and analyses of DNA and RNA. The results of the present investigation confirm the findings of previous studies that these changes to a considerable extent are reversible after removal of the outflow obstruction. This seems to be true both in animals obstructed for a short period of time (10 days) and in animals where the hypertrophy and hyperplasia processes have diminished (six weeks). (J. Urol., 140:642–646, 1988) © 1988 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byKOFF S, GIGAX M and JAYANTHI V (2018) NOCTURNAL BLADDER EMPTYING:: A SIMPLE TECHNIQUE FOR REVERSING URINARY TRACT DETERIORATION IN CHILDREN WITH NEUROGENIC BLADDERJournal of Urology, VOL. 174, NO. 4 Part 2, (1629-1632), Online publication date: 1-Oct-2005.KOFF S, MUTABAGANI K and JAYANTHI V (2018) THE VALVE BLADDER SYNDROME: PATHOPHYSIOLOGY AND TREATMENT WITH NOCTURNAL BLADDER EMPTYINGJournal of Urology, VOL. 167, NO. 1, (291-297), Online publication date: 1-Jan-2002.CHAI T, GEMALMAZ H, ANDERSSON K, TUTTLE J and STEERS W (2018) PERSISTENTLY INCREASED VOIDING FREQUENCY DESPITE RELIEF OF BLADDER OUTLET OBSTRUCTIONJournal of Urology, VOL. 161, NO. 5, (1689-1693), Online publication date: 1-May-1999.Kojima M, Inui E, Ochiai A, Naya Y, Kamoi K, Ukimura O and Watanabe H (2018) Reversible Change of Bladder Hypertrophy Due to Benign Prostatic Hyperplasia After Surgical Relief of ObstructionJournal of Urology, VOL. 158, NO. 1, (89-93), Online publication date: 1-Jul-1997.Zderic S, Rohrmann D, Gong C, Synder H, Duckett J, Wein A and Levin R (2018) The Decompensated Detrusor II: Evidence for Loss of Sarcoplasmic Reticulum Function After Bladder Outlet Obstruction in the RabbitJournal of Urology, VOL. 156, NO. 2S, (587-592), Online publication date: 1-Aug-1996.Igawa Y, Persson K, Andersson K, Uvelius B and Mattiasson A (2018) Facilitatory Effect of Vasoactive Intestinal Polypeptide on Spinal and Peripheral Micturition Reflex Pathways in Conscious Rats with and without Detrusor InstabilityJournal of Urology, VOL. 149, NO. 4, (884-889), Online publication date: 1-Apr-1993.Malmgren A, Uvelius B, Andersson K and Andersson P (2018) On the Reversibility of Functional Bladder Changes Induced by Infra Vesical Outflow Obstruction in the RatJournal of Urology, VOL. 143, NO. 5, (1026-1031), Online publication date: 1-May-1990. Volume 140Issue 3September 1988Page: 642-646 Advertisement Copyright & Permissions© 1988 by The American Urological Association Education and Research, Inc.MetricsAuthor Information P. Lindnér More articles by this author A. Mattiasson More articles by this author L. Persson More articles by this author B. Uvelius More articles by this author Expand All Advertisement PDF downloadLoading ...