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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Anterior temporal lobectomy versus selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy

2015; Thieme Medical Publishers (Germany); Volume: 74; Issue: 1 Linguagem: Inglês

10.1590/0004-282x20150188

ISSN

1678-4227

Autores

Fábio A. Nascimento, Luana Antunes Maranha Gatto, Carlos Eduardo Silvado, Maria Joana Mäder-Joaquim, Marlus S. Moro, João Cândido Araújo,

Tópico(s)

Pharmacological Effects and Toxicity Studies

Resumo

To contribute our experience with surgical treatment of patients with mesial temporal lobe epilepsy (mTLE) undergoing anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SelAH).This is a retrospective observational study. The sample included patients with medically refractory mTLE due to unilateral mesial temporal sclerosis who underwent either ATL or SelAH, at Hospital de Clinicas - UFPR, from 2005 to 2012. We report seizure outcomes, using Engel classification, cognitive outcomes, using measurements of verbal and visuospatial memories, as well as operative complications.Sixty-seven patients (33 ATL, 34 SelAH) were studied; median follow-up was 64 months. There was no statistically significant difference in seizure or neuropsychological outcomes, although verbal memory was more negatively affected in ATL operations on patients' dominant hemispheres. Higher number of major complications was observed in the ATL group (p = 0.004).Seizure and neuropsychological outcomes did not differ. ATL appeared to be associated with higher risk of complications.

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