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Association between Serum Potassium and Outcomes in Patients with Reduced Kidney Function

2015; Lippincott Williams & Wilkins; Volume: 11; Issue: 1 Linguagem: Inglês

10.2215/cjn.01730215

1555-905X

Jiacong Luo, Steven M. Brunelli, Donna E. Jensen, Alex Yang,

Magnesium in Health and Disease

Patients with CKD are more likely than others to have abnormalities in serum potassium (K(+)). Aside from severe hyperkalemia, the clinical significance of K(+) abnormalities is not known. We sought to examine the association of serum K(+) with mortality and hospitalization rates within narrow eGFR strata to understand how the burden of hyperkalemia varies by CKD severity. Associations were examined between serum K(+) and discontinuation of medications that block the renin-angiotensin-aldosterone system (RAAS), which are known to increase serum K(+).