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Biocompatibility of new Ti–Nb–Ta base alloys

2015; Elsevier BV; Volume: 61; Linguagem: Inglês

10.1016/j.msec.2015.12.071

1873-0191

Abdelrahman Hussein, Lamiaa Z. Mohamed, Mohammed K. Gouda, A. Hefnawy, Sherif Kandil,

Bone Tissue Engineering Materials

β-type titanium alloys are promising materials in the field of medical implants. The effect of β-phase stability on the mechanical properties, corrosion resistance and cytotoxicity of a newly designed β-type (Ti77Nb17Ta6) biocompatible alloys are studied. The β-phase stability was controlled by the addition of small quantities of Fe and O. X-ray diffraction and microstructural analysis showed that the addition of O and Fe stabilized the β-phase in the treated solution condition. The strength and hardness have increased with the increase in β-phase stability while ductility and Young's modulus have decreased. The potentio-dynamic polarization tests showed that the corrosion resistance of the new alloys is better than Ti-6Al-4V alloy by at least ten times. Neutral red uptake assay cytotoxicity test showed cell viability of at least 95%. The new alloys are promising candidates for biomedical applications due to their high mechanical properties, corrosion resistance, and reduced cytotoxicity.