Produção Nacional
Avaliação de dermocosmético com retinaldeído, nicotinamida e vitis vinifera no fotoenvelhecimento cutâneo de mulheres entre 25 e 40 anos de idade
2012; Sociedade Brasileira de Dermatologia; Volume: 4; Issue: 1 Linguagem: Inglês
ISSN
1984-8773
AutoresLúcia Helena Fávaro Arruda, Ana Carolina Belini Bazán Arruda, Paula Luz Stocco, Fernanda Sayuri Ota, Elvira Cancio Assumpção, Sthephani S.B. Langen, Adilson Costa, Un Sun Park, Carla A. H.V. Myashiro,
Tópico(s)Dermatologic Treatments and Research
ResumoThe skin is subject to intrinsic and extrinsic aging processes, which makes treating cutaneous photoaging clinically challenging. Objective:To use objective and subjective parameters to evaluate the safety, tolerability, and clinical efficacy of a cosmetic product containing 0.05% retinaldehyde, 4% nicotinamide, and 1% Vitis vinifera extract in the treatment of skin aging. Methods: A monocentric, prospective, open study evaluated 40 female volunteers (25-40 years old) with Fitzpatrick skin types I to IV, who used the dermocosmetic product for 60 consecutive days. Subjective assessments were carried out by the physician and the volunteer patients. In addition, ultrasound examination and objective assessment of photographic records using the Visia® imaging system, skin biopsies, corneometry, pH metry, and sebumetry were conducted. Results: Thirty-six volunteers completed the study. Subjective evaluations revealed improvements in wrinkles, fine lines, sagging, vitality, and overall appearance. Ultrasound and skin biopsies showed increased collagen (94.4% and 30.6%, respectively). Pictures from the Visia® device demonstrated a reduction in stains, wrinkles, and pores, and improvements in the skin’s texture. Sebumetry revealed a decrease in the oiliness and the pH. Measurements taken with the corneometer remained constant. Conclusions: This dermocosmetic product is effective and safe in the treatment of photoaging
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