Basolateral but not corticomedial amygdala shows neuroarchitectural changes in schizophrenia
2016; Wiley; Volume: 94; Issue: 6 Linguagem: Inglês
10.1002/jnr.23683
ISSN1097-4547
AutoresMatthew Williams, Seema Pattni, R. K. B. Pearce, Steven R. Hirsch, Michael Maier,
Tópico(s)Tryptophan and brain disorders
ResumoJournal of Neuroscience ResearchVolume 94, Issue 6 p. 544-547 Letter to the Editor Basolateral but not corticomedial amygdala shows neuroarchitectural changes in schizophrenia Matthew Roy Williams, Corresponding Author Matthew Roy Williams Robert Steiner Unit, Hammersmith Hospital, London, United KingdomCorrespondence to: Dr. Matthew Williams, Robert Steiner Unit, Hammersmith Hospital, London, W12 0NN United Kingdom. E-mail: matthew.r.williams@imperial.ac.ukSearch for more papers by this authorSeema Pattni, Seema Pattni Mersey Deanery for General Practice, Health Education North West, Liverpool, United KingdomSearch for more papers by this authorRonald Keith Pearce, Ronald Keith Pearce Claybrook Centre, Imperial College, London, United KingdomSearch for more papers by this authorSteven Richard Hirsch, Steven Richard Hirsch Claybrook Centre, Imperial College, London, United KingdomSearch for more papers by this authorMichael Maier, Michael Maier Trust HQ, West London Mental Health NHS Trust, Southall, Middlesex, United KingdomSearch for more papers by this author Matthew Roy Williams, Corresponding Author Matthew Roy Williams Robert Steiner Unit, Hammersmith Hospital, London, United KingdomCorrespondence to: Dr. Matthew Williams, Robert Steiner Unit, Hammersmith Hospital, London, W12 0NN United Kingdom. E-mail: matthew.r.williams@imperial.ac.ukSearch for more papers by this authorSeema Pattni, Seema Pattni Mersey Deanery for General Practice, Health Education North West, Liverpool, United KingdomSearch for more papers by this authorRonald Keith Pearce, Ronald Keith Pearce Claybrook Centre, Imperial College, London, United KingdomSearch for more papers by this authorSteven Richard Hirsch, Steven Richard Hirsch Claybrook Centre, Imperial College, London, United KingdomSearch for more papers by this authorMichael Maier, Michael Maier Trust HQ, West London Mental Health NHS Trust, Southall, Middlesex, United KingdomSearch for more papers by this author First published: 11 January 2016 https://doi.org/10.1002/jnr.23683Citations: 5 SIGNIFICANCE: This article describes a methodological pilot study counted with neuropathological techniques examining neurons of the amygdala in schizophrenia and depression against matched control cases. The study initially sought to test methods measuring the overall shape and size of certain neuron types and their nuclei and nucleoli. A randomly selected cohort of cells was identified by their physical characteristics in two functionally separate areas of the amygdala that are of key interest because these, roughly, are the input and output regions of the amygdala, a structure critically involved in limbic regulation. Changes were observed only in schizophrenia in one particular functional region. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume94, Issue6Special Issue: The Amygdala: Dysfunction, Hyperfunction and ConnectivityJune 2016Pages 544-547 RelatedInformation
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