Structure determination of a novel cyclic phosphocompound isolated from Desulfovibrio desulfuricans
1992; Portland Press; Volume: 285; Issue: 2 Linguagem: Inglês
10.1042/bj2850387
ISSN1470-8728
AutoresDavid L. Turner, Helena Santos, Paula Fareleira, Isabel Pacheco, Jean LeGall, António V. Xavier,
Tópico(s)DNA and Nucleic Acid Chemistry
ResumoThe structure of a novel diphosphodiester compound recently detected in Desulfovibrio desulfuricans cells [Santos, Fareleira, Pedregal, LeGall & Xavier (1991) Eur. J. Biochem. 201, 283-287] was fully elucidated using a combination of n.m.r. techniques in aqueous and in methanolic solutions. The novel metabolite was identified as 3-methyl-1,2,3,4-tetrahydroxybutane-1,3-cyclic bisphosphate, and the minimum energy conformation is presented. The two chiral centres have the relative configuration RS.
Referência(s)