Single nucleotide polymorphisms in TP53 but not KRAS or MDM2 are predictive of clinical outcome in multiple myeloma treated with high-dose melphalan and autologous stem cell support
2015; Taylor & Francis; Volume: 57; Issue: 6 Linguagem: Inglês
10.3109/10428194.2015.1099648
ISSN1042-8194
AutoresNiklas Gebauer, Harald Biersack, Ann-Cathrin Czerwinska, Janina Schemme, Tim Tristan Hardel, Veronica Bernard, Dirk Rades, Hendrik Lehnert, Kim Luley, Christoph Thorns,
Tópico(s)Chronic Lymphocytic Leukemia Research
ResumoSingle-nucleotide polymorphisms (SNPs) of TP53 (codon 72, rs1042522), KRAS (LCS6 3’UTR, rs 61764370) and MDM2 promoter (SNP 309, rs2279744) have been associated with risk for various human cancers ...
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