Fluorescent Nanorods and Nanospheres for Real‐Time In Vivo Probing of Nanoparticle Shape‐Dependent Tumor Penetration
2011; Wiley; Volume: 123; Issue: 48 Linguagem: Inglês
10.1002/ange.201104449
ISSN1521-3757
AutoresVikash P. Chauhan, Zoran Popović, Ou Chen, Jian Cui, Dai Fukumura, Moungi G. Bawendi, Rakesh K. Jain,
Tópico(s)Advanced biosensing and bioanalysis techniques
ResumoAngewandte ChemieVolume 123, Issue 48 p. 11619-11622 Zuschrift Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration† Vikash P. Chauhan, Vikash P. Chauhan Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA) Harvard School of Engineering and Applied Sciences, Harvard University (USA) These authors contributed equally to this work.Search for more papers by this authorDr. Zoran Popović, Dr. Zoran Popović Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) These authors contributed equally to this work.Search for more papers by this authorDr. Ou Chen, Dr. Ou Chen Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA)Search for more papers by this authorJian Cui, Jian Cui Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA)Search for more papers by this authorProf. Dr. Dai Fukumura, Prof. Dr. Dai Fukumura Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA)Search for more papers by this authorProf. Dr. Moungi G. Bawendi, Corresponding Author Prof. Dr. Moungi G. Bawendi mgb@mit.edu Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) Moungi G. Bawendi, Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) Rakesh K. Jain, Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA)Search for more papers by this authorProf. Dr. Rakesh K. Jain, Corresponding Author Prof. Dr. Rakesh K. Jain jain@steele.mgh.harvard.edu Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA) Moungi G. Bawendi, Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) Rakesh K. Jain, Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA)Search for more papers by this author Vikash P. Chauhan, Vikash P. Chauhan Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA) Harvard School of Engineering and Applied Sciences, Harvard University (USA) These authors contributed equally to this work.Search for more papers by this authorDr. Zoran Popović, Dr. Zoran Popović Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) These authors contributed equally to this work.Search for more papers by this authorDr. Ou Chen, Dr. Ou Chen Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA)Search for more papers by this authorJian Cui, Jian Cui Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA)Search for more papers by this authorProf. Dr. Dai Fukumura, Prof. Dr. Dai Fukumura Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA)Search for more papers by this authorProf. Dr. Moungi G. Bawendi, Corresponding Author Prof. Dr. Moungi G. Bawendi mgb@mit.edu Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) Moungi G. Bawendi, Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) Rakesh K. Jain, Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA)Search for more papers by this authorProf. Dr. Rakesh K. Jain, Corresponding Author Prof. Dr. Rakesh K. Jain jain@steele.mgh.harvard.edu Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA) Moungi G. Bawendi, Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge MA 02139 (USA) Rakesh K. Jain, Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St., Boston, MA 02114 (USA)Search for more papers by this author First published: 06 October 2011 https://doi.org/10.1002/ange.201104449Citations: 26 † We thank Debby Pheasant (BIF Facility, MIT), Julia Kahn (MGH), and Sylvie Roberge (MGH) for technical assistance. This research was supported by the U.S. National Cancer Institute grants R01-CA126642 (R.K.J. and M.G.B.), R01-CA085140, R01-CA115767 (R.K.J.), P01-CA080124 (R.K.J. and D.F.), R01-CA096915 (D.F.); by the U.S. Department of Defense Breast Cancer Research Program Innovator Award W81XWH-10-1-0016 (R.K.J.); by the MIT-Harvard NIH Center for Cancer Nanotechnology Excellence 1U54-CA119349 (M.G.B.); by the MIT DCIF CHE-980806, DBI-9729592; by the ISN W911NF-07-D-0004 (M.G.B); by the NSF-MRSEC program (DMR-0117795) via the use of its shared user facilities. Read the full textAboutPDF ToolsRequest permissionAdd to favorites ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Formabhängig: Bei fluoreszierenden Quantenpunkt-Nanokügelchen und -stäbchen mit identischen hydrodynamischen Größen und Oberflächeneigenschaften, aber unterschiedlichen Aspektverhältnissen zeigen bei der In-vivo-Echtzeitbildgebung von Brustkrebstumoren die Nanostäbchen eine schnellere Verteilung als Nanokügelchen vergleichbarer Plasmahalbwertszeit. Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description ange_201104449_sm_miscellaneous_information.pdf633.5 KB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume123, Issue48November 25, 2011Pages 11619-11622 This is the German version of Angewandte Chemie. Note for articles published since 1962: Do not cite this version alone. Take me to the International Edition version with citable page numbers, DOI, and citation export. We apologize for the inconvenience. RelatedInformation
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