Produção Nacional
Revisado por pares
Phytochemical screening, antioxidant and antibacterial activities of extracts prepared from different tissues of Schinus terebinthifolius Raddi that occurs in the coast of Bahia, Brazil
2015; SAGE Publishing; Volume: 11; Issue: 43 Linguagem: Inglês
10.4103/0973-1296.160459
ISSN0976-4062
AutoresPaulo R. Ribeiro, Luzimar Gonzaga Fernandez, MartaBruno Loureiro, RafaelConceição Simões, Renato Delmondez de Castro, CinaraOliveira D′Sousa′ Costa,
Tópico(s)Phytochemicals and Medicinal Plants
ResumoPharmacognosy Magazine,2015,11,43,607-614.DOI:10.4103/0973-1296.160459Published:July 2015Type:Original ArticleAuthors:Cinara Oliveira D'Sousa' Costa, Paulo Roberto Ribeiro, Marta Bruno Loureiro, Rafael Conceição Simões, Renato Delmondez de Castro, and Luzimar Gonzaga Fernandez Author(s) affiliations:Cinara Oliveira D'Sousa' Costa† , Paulo Roberto Ribeiro† , Marta Bruno Loureiro, Rafael Conceição Simões, Renato Delmondez de Castro, Luzimar Gonzaga Fernandez Laboratory of Biochemistry, Biotechnology and Bioproducts (LBBB), Department of Biofunction, Health Sciences Institute, Federal University of Bahia (UFBA), Brazil Abstract:Background: Schinus terebinthifolius is widely used in traditional medicine by Brazilian quilombola and indigenous communities for treatment of several diseases. Extracts from different tissues are being used to produce creams to treat cervicitis and cervicovaginitis. However, most studies are limited to the assessment of the essential oils and extracts obtained from the leaves. Objective: The aim was to evaluate antioxidant and antibacterial activities, to assess the phytochemical profile and to quantify total phenolic compounds of various extracts prepared from S. terebinthifolius grown in the coast of Bahia, Brazil. Materials and Methods: Extracts were obtained by hot continuous extraction (soxhlet) and by maceration. Quantification of phenolic compounds was performed using the Folin‑Ciocalteu method and antioxidant properties were assessed by 2,2‑diphenyl‑1‑picrylhydrazyl radical scavenging assay. Phytochemical screening was performed as described by in the literature and antibacterial activity against Enterococcus faecalis (ATCC 29212) was determined by the microdilution broth assay. Results: Extraction method greatly affected the metabolite profile of the extracts. Antioxidant activity varied between 21.92% and 85.76%, while total phenols ranged between 5.44 and 309.03 mg EAG/g of extract. Leaf extract obtained with soxhlet showed minimum inhibitory concentration (MIC) of 15.62 μg/mL, while stem extract obtained by maceration was able to inhibit the growth of E. faecalis at 62.5 μg/mL. Stem bark extracts showed a MIC of 500 μg/mL for both extraction methods, while no inhibition was observed for fruit extracts. Conclusion: In general, total phenolic content, antioxidant and antibacterial activities were higher in samples obtained by soxhlet. Our results provide important clues in order to identify alternative sources of bioactive compounds that can be used to develop new drugs. Keywords:Aroeira vermelha, Bioactive compounds, Brazilian species, medicinal properties, quilombola communitiesView:PDF (1.21 MB) Full Text
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