Revisão Revisado por pares

Tropheryma whipplei infection and Whipple's disease

2016; Elsevier BV; Volume: 16; Issue: 3 Linguagem: Inglês

10.1016/s1473-3099(15)00537-x

ISSN

1474-4457

Autores

Thomas Marth, Verena Moos, Christian Müller, Federico Biagi, Thomas Schneider,

Tópico(s)

Whipple's Disease and Interleukins

Resumo

Recent advances in medical microbiology, epidemiology, cellular biology, and the availability of an expanded set of diagnostic methods such as histopathology, immunohistochemistry, PCR, and bacterial culture have improved our understanding of the clinical range and natural course of Tropheryma whipplei infection and Whipple's disease. Interdisciplinary and transnational research activities have contributed to the clarification of the pathogenesis of the disorder and have enabled controlled trials of different treatment strategies. We summarise the current knowledge and new findings relating to T whipplei infection and Whipple's disease.

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