Artigo Acesso aberto Revisado por pares

Differential Effects of Teriparatide and Denosumab on Intact PTH and Bone Formation Indices: AVA Osteoporosis Study

2016; Oxford University Press; Volume: 101; Issue: 4 Linguagem: Inglês

10.1210/jc.2015-4181

ISSN

1945-7197

Autores

David W. Dempster, Hua Zhou, Robert R. Recker, Jacques P. Brown, Christopher Recknor, E. Michael Lewiecki, Paul D. Miller, Sudhaker D. Rao, David L. Kendler, R. Lindsay, John H. Krege, Jahangir Alam, Kathleen A. Taylor, Boris Janos, Valerie A. Ruff,

Tópico(s)

Bone Metabolism and Diseases

Resumo

We compared effects of teriparatide and denosumab on PTH, bone turnover markers, and bone histomorphometry in osteoporotic postmenopausal women. The findings were inconsistent with an early indirect anabolic effect of denosumab.

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