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Hyphenated Techniques and Their Applications in Natural Products Analysis

2012; Springer Science+Business Media; Linguagem: Inglês

10.1007/978-1-61779-624-1_12

1940-6029

Satyajit D. Sarker, Lutfun Nahar,

Essential Oils and Antimicrobial Activity

A technique where a separation technique is coupled with an online spectroscopic detection technology is known as hyphenated technique, e.g., GC–MS, LC–PDA, LC–MS, LC–FTIR, LC–NMR, LC–NMR–MS, and CE–MS. Recent advances in hyphenated analytical techniques have remarkably widened their applications to the analysis of complex biomaterials, especially natural products. This chapter focuses on the applications of hyphenated techniques to pre-isolation and isolation of natural products, dereplication, online partial identification of compounds, chemotaxonomic studies, chemical finger-printing, quality control of herbal products, and metabolomic studies, and presents specific examples. However, a particular emphasis has been given on the hyphenated techniques that involve an LC as the separation tool.