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BIBTEX RIS

Clinical and molecular update of a large cohort followed by the Brazilian MODY multicenter study group (BRASMODY)

2015; BioMed Central; Volume: 7; Issue: S1 Linguagem: Inglês

10.1186/1758-5996-7-s1-a212

ISSN

1758-5996

Autores

Fernando de Mello Almada Giuffrida, Letícia Schwerz Weinert, Regina S. Moisés, Luís Eduardo Calliari, Thaís Della Manna, Lílian Araújo Caetano, Milena Gurgel Teles, Renata P. Dotto, Ilda S. Kunii, Sandra Pinho Silveiro, Magnus R. Dias‐da‐Silva, André F. Reis,

Tópico(s)

Diabetes and associated disorders

Resumo

Background Maturity-Onset Diabetes of the Young (MODY) is a group of monogenic forms of diabetes mellitus (DM) caused by mutations in at least 13 genes. Mutations in Glucokinase (GCK) and Hepatocyte nuclear factor-1 homeobox A (HNF1A) are the most common. Frequency of subtypes varies according to studied population. A broader view of MODY in Brazil is needed to improve diagnosis, epidemiological registry, and clinical care, also paving the way for future research.

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