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Causes of Fever in Rural Southern Laos

2015; American Society of Tropical Medicine and Hygiene; Volume: 93; Issue: 3 Linguagem: Inglês

10.4269/ajtmh.14-0772

1476-1645

Mayfong Mayxay, Onanong Sengvilaipaseuth, Anisone Chanthongthip, Audrey Dubot‐Pérès, Jean‐Marc Rolain, Philippe Parola, Scott B. Craig, Suhella M. Tulsiani, Mary‐Anne Burns, Maniphone Khanthavong, Siamphay Keola, Tiengkham Pongvongsa, Didier Raoult, Sabine Dittrich, Paul N. Newton,

Vector-borne infectious diseases

The etiology of fever in rural Lao People's Democratic Republic (Laos) has remained obscure until recently owing to the lack of laboratory facilities. We conducted a study to determine the causes of fever among 229 patients without malaria in Savannakhet Province, southern Laos; 52% had evidence of at least one diagnosis (45% with single and 7% with apparent multiple infections). Among patients with only one diagnosis, dengue (30.1%) was the most common, followed by leptospirosis (7.0%), Japanese encephalitis virus infection (3.5%), scrub typhus (2.6%), spotted fever group infection (0.9%), unspecified flavivirus infection (0.9%), and murine typhus (0.4%). We discuss the empirical treatment of fever in relation to these findings.