Severe Cutaneous Adverse Reactions to Drugs (SCAR): Definitions, Diagnostic Criteria, Genetic Predisposition
2009; Volume: 27; Issue: 4 Linguagem: Inglês
10.29784/ds.200912.0001
AutoresJean‐Claude Roujeau, L. Allanore, Yvonne Liß, Maja Mockenhaupt,
Tópico(s)Autoimmune Bullous Skin Diseases
ResumoThis paper is a review of the clinical characteristics, diagnostic criteria and main drug causes of the severe cutaneous adverse reactions to drugs (SCAR) that are studied by the RegiS-CAR-group. These include acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (also called drug-induced hypersensitivity syndrome), Stevens-Johnson syndrome, and toxic epidermal necrolysis.
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