Perfluorocarbon‐Loaded Hollow Bi 2 Se 3 Nanoparticles for Timely Supply of Oxygen under Near‐Infrared Light to Enhance the Radiotherapy of Cancer
2016; Volume: 28; Issue: 14 Linguagem: Inglês
10.1002/adma.201504617
ISSN1521-4095
AutoresGuosheng Song, Chao Liang, Xuan Yi, Qi Zhao, Liang Cheng, Kai Yang, Zhuang Liu,
Tópico(s)Electronic and Structural Properties of Oxides
ResumoHollow Bi2 Se3 nanoparticles prepared by a cation exchange method are loaded with perfluorocarbon as an oxygen carrier. With these nanoparticles, a promising concept is demonstrated to enhance radiotherapy by not only using their X-ray-absorbing ability to locally concentrate radiation energy in the tumor, but also employing near-infrared light to trigger burst release of oxygen from the nanoparticles to overcome hypoxia-associated radio-resistance.
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