Voltar
Revisão Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Subcortical ischemic vascular disease and cognition: A systematic review

2008; Associação Neurologia Cognitiva e do Comportamento; Volume: 2; Issue: 2 Linguagem: Inglês

10.1590/s1980-57642009dn20200002

ISSN

1980-5764

Autores

Gilberto Sousa Alves, Carlos Eduardo de Oliveira Alves, Maria Elisa Lanna, Denise Madeira Moreira, Eliasz Engelhardt, Jerson Laks,

Tópico(s)

Neurological Disease Mechanisms and Treatments

Resumo

Abstract Subcortical Ischemic Vascular Disease (SIVD) is underdiagnosed. This review investigates the relationship among SIVD severity, cognitive status and neuroimaging markers. Methods: Cohort, cross-sectional and case control studies were searched on ISI, Medline, Scielo, PsychoInfo and LILACS databases published between 1995 and 2006. Results: The most impaired cognitive domains were executive, attentional and memory retrieval mechanisms. These cognitive features were frequently associated to White Matter Lesions (WML). Conclusions: WML is an independent factor in cognitive decline. However, the threshold for this impact is not yet clearly established.

Referência(s)