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Creole cattle from northwestern Mexico has high genetic diversity in the locus DRB3.2

2015; Cambridge University Press; Volume: 57; Linguagem: Inglês

10.1017/s2078633615000211

2078-6344

I. Fernández, Ivan Leyva-Baca, Felipe Alonso Rodríguez-Almeida, Raúl Ullóa-Arvízu, José Gonzalo Ríos-Ramírez, Amanda Gayosso-Vázquez, Rogelio A. Alonso-Morales,

Animal Disease Management and Epidemiology

Summary The objective of this study was to determine the genetic diversity of creole cattle in northwestern Mexico using the BoLA-DRB3.2 locus of the Major Histocompatibility Complex (MHC). A total of 56 creole cattle were sampled from five communities; in the state of Chihuahua (Cerocahui, Guadalupe y Calvo and Cuauhtémoc) and in the state of Baja California Sur (La Paz and Mulegé). The BoLA-DRB3.2 locus was genotyped by PCR-RFLP assay. Thirty-nine alleles were identified, out of which 14 had not been previously reported. The average level of inbreeding in all populations analyzed was F IS = 0.09 ( P < 0.0001), but only two populations (Cerocahui and Guadalupe y Calvo) showed an excess of homozygotes ( P < 0.05). The breed differentiation in all populations studied was F SC = 0.068 ( P < 0.0001). The smallest genetic distance was between La Paz and Mulegé (0.022); but Mulegé presented smaller distances (0.028–0.053) with the populations of La Paz (0.071–0.083) and with Chihuahua. Baja California Sur populations are grouped in a separate branch than Chihuahua populations. We conclude that creole cattle from Baja California Sur and Chihuahua show high genetic diversity in the locus BoLA-DRB3.2.