A new flavone C -glycoside and a new bibenzyl from Bulbophyllum retusiusculum
2016; Taylor & Francis; Volume: 30; Issue: 14 Linguagem: Inglês
10.1080/14786419.2015.1126266
ISSN1478-6427
AutoresMinghui Yang, Yun-Shan Fang, Le Cai, Ying Li, Jianwei Dong, Tianpeng Yin, Caili Huang, Zhong‐Tao Ding,
Tópico(s)Bioactive natural compounds
ResumoAbstractA new flavone C-glycoside, apigenin 6-C-α-arabinofuranosyl 8-C-α-arabinopyranoside (1) and a new bibenzyl, bulbotetusine (2), were isolated from the tubers of Bulbophyllum retusiusculum. Their structures were established on the basis of extensive spectroscopic analyses. The absolute configuration of 2 was determined by the comparison of experimental and calculated electronic circular dichroism. Compounds 1 and 2 showed no obvious cytotoxic activity against any five human tumour cell lines with IC50 values >40 μM.Keywords: Bulbophyllum retusiusculumflavone C-glycosidebibenzylapigenin 6-C-α-arabinofuranosyl 8-C-α-arabinopyranosidebulbotetusine Disclosure statementNo potential conflict of interest was reported by the authors.FundingThis work was financially supported with a grant from the National Natural Science Foundation of China [grant number 81160393].
Referência(s)