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1,4-ADDITION OF Ν,N-DIALKYLPHENYLACETAMIDES TO METHYLENE SUBSTITUTED 1,3-DIHYDRO-3-METHYLENE- 2H-INDOL-2-ONES

2005; De Gruyter; Volume: 11; Issue: 2 Linguagem: Inglês

10.1515/hc.2005.11.2.181

2191-0197

Tzvetanka P. Cholakova, Aleksey Vasilev, Nina Ninjo, A. Dobrev,

Organic and Inorganic Chemical Reactions

Two 3-methylene-2H-indol-2-ones substituted in the methylene group by either a phenyl 6 or two electron withdrawing groups 8 react with the lithium enolates of Ν,Ν-disubstituted phenylacetamides and 2H-indol-2-one giving the corresponding products of conjugate 1,4-addition -the l,3-dihydro-indol-2-ones 7 and 9.