A ratiometric fluorescence probe based on a novel FRET platform for imaging endogenous HOCl in the living cells
2016; Elsevier BV; Volume: 229; Linguagem: Inglês
10.1016/j.snb.2016.01.146
ISSN1873-3077
AutoresYanru Zhang, Zhimin Zhao, Jun‐Ying Miao, Bao‐Xiang Zhao,
Tópico(s)Nitric Oxide and Endothelin Effects
ResumoA ratiometric fluorescence probe (CARSH) was designed on a novel FRET platform for HOCl. The novel platform enlarged spectral overlap between the donor emission band and the acceptor absorption band comparing to the traditional coumarin–rhodamine FRET platform, and the energy transfer reached up to 81.1%. The probe showed high selectivity, excellent sensitivity, fast response, good membrane permeability and stability.
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