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Effect of different fluoride varnishes on remineralization of artificial enamel carious lesions

2016; Wiley; Volume: 27; Issue: 3 Linguagem: Inglês

10.1111/ipd.12243

1365-263X

Siti N. B. Mohd Said, Manikandan Ekambaram, Cynthia Kar Yung Yiu,

Oral microbiology and periodontitis research

Objectives To compare remineralization potential of topical fluoride varnishes with added calcium phosphate‐based delivery systems on artificial enamel caries. Methods Human enamel specimens ( n = 60) were randomly divided into six groups: Group 0: Control (no varnish), Group 1: Duraphat ® , Group 2: MI Varnish ™ , Group 3: Embrace ™ Varnish, Group 4: Enamel Pro ® Varnish, and Group 5: Clinpro ™ White Varnish. Specimens were immersed in demineralizing solution for 96 h to create artificial caries lesion. Each specimen was then immersed in artificial saliva for 6 h after fluoride varnish application and pH cycling was performed for 8 days. Specimens were evaluated using Knoop surface microhardness ( KHN ) and transverse microradiography ( TMR ). One‐way anova test was performed to examine the effect of fluoride varnishes on change in percentage of surface hardness recovery (% SHR ), change in lesion depth (Δ LD ), and change in mineral loss (ΔΔ Z ) with the significance limit set at 5%. Results % SHR of enamel following treatment with Group 1 was significantly higher than Group 3 and Group 4. Conversely, Δ LD and ΔΔ Z of Group 1 were significantly higher than Group 2, Group 3, and Group 4. No significant differences in % SHR , Δ LD , and ΔΔ Z were found between Group 1 and Group 5. Conclusions Duraphat ® alone achieves significant remineralization of enamel carious lesions. Clinpro ™ White Varnish had similar enamel remineralization effect as Duraphat ® .