
EMERGENCE OF A NEW ARBOVIRUS DISEASE IN BRAZIL
1978; Oxford University Press; Volume: 108; Issue: 5 Linguagem: Inglês
10.1093/oxfordjournals.aje.a112637
ISSN1476-6256
AutoresÓscar Lopes, LIA DE ABREU SACCHETTA, Terezinha Lisieux Moraes Coimbra, Geraldo Henriques Pinto, Carmen Moreno Glasser,
Tópico(s)Mosquito-borne diseases and control
ResumoIn April, 1975, an outbreak of human encephalitis caused by Rocio virus, a new flavivirus, occurred in the coastal region of southern São Paulo, Brazil. The epidemic started during the second half of March, 1975, and ended in June, 1975. A total of 465 cases with 61 deaths were recorded, and the overall attack rate was 15 per thousand population. The mortality rate was two per thousand inhabitants and the overall case-fatality rate was 13%. However, the case-fatality rate was markedly decreased when adequate hospital care was provided. The number of cases in the 15--30 years age group was higher than in the other age groups and the rate was higher in males than in females. Lack of evidence of person-to-person transmission, based on a study of families involved in the epidemic and on the antigenic relationship to other mosquito-borne flaviviruses, suggested that the virus was transmitted by a vector and that wild animals were involved in the virus cycle.
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