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BIBTEX RIS

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

2016; American Association for the Advancement of Science; Volume: 9; Issue: 415 Linguagem: Inglês

10.1126/scisignal.aad1884

ISSN

1937-9145

Autores

Sébastien Viel, Antoine Marçais, Fernando Guimarães, Róisín M. Loftus, Jessica Rabilloud, Morgan Grau, Sophie Degouve, Sophia Djebali, Amélien Sanlaville, Emily Charrier, Jacques Bienvenu, Julien C. Marie, Christophe Caux, Jacqueline Marvel, Liam Town, Nicholas D. Huntington, Laurent Bartholin, David K. Finlay, Mark J. Smyth, Thierry Walzer,

Tópico(s)

Immune cells in cancer

Resumo

Blocking TGF-β signaling in natural killer cells enhances their metabolism and ability to kill tumor cells.

Referência(s)