Fluoroquinolone and Third-Generation-Cephalosporin Resistance among Hospitalized Patients with Urinary Tract Infections Due to Escherichia coli: Do Rates Vary by Hospital Characteristics and Geographic Region?
2016; American Society for Microbiology; Volume: 60; Issue: 5 Linguagem: Inglês
10.1128/aac.02505-15
ISSN1098-6596
AutoresMonique R. Bidell, Melissa Palchak, John Mohr, Thomas P. Lodise,
Tópico(s)Pediatric Urology and Nephrology Studies
ResumoThis analysis of nearly 10,000 hospital-associated urinary tract infection (UTI) episodes due to Escherichia coli showed that fluoroquinolone and third-generation-cephalosporin resistance rates were 34.5% and 8.6%, respectively; the rate of concurrent resistance to both agents was 7.3%. Fluoroquinolone resistance rates exceeded 25% regardless of geographic location or hospital characteristics. The findings suggest that fluoroquinolones should be reserved and third-generation cephalosporins be used with caution as empirical agents for hospitalized patients with UTIs due to E. coli.
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