Predicting outcome of antipsychotic drug treatment from early response
1980; American Psychiatric Association; Volume: 137; Issue: 9 Linguagem: Inglês
10.1176/ajp.137.9.1088
ISSN1535-7228
AutoresPhilip R. A. May, Theodore Van Putten, Coralee Yale,
Tópico(s)Bipolar Disorder and Treatment
ResumoBack to table of contents Previous article Next article No AccessPredicting outcome of antipsychotic drug treatment from early responsePublished Online:1 Apr 2006https://doi.org/10.1176/ajp.137.9.1088AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractThe authors gave 48 newly admitted schizophrenic patients an initial test dose (2.2 mg/kg) of chlorpromazine hydrochloride and additional doses at 24 and 36 hours. Clinical response was measured at 48 hours and at the end of subsequent treatment with a fixed dose (6.6 mg/kg) of chlorpromazine. There was a consistent correlation between 48-hour change and the eventual amount of improvement by the end of drug treatment for all 10 outcome criteria. The authors conclude that change early on in drug treatment is a useful predictor of outcome. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byEarly Markers in Resistant Schizophrenia: Effect of the First Antipsychotic Drug25 March 2022 | Diagnostics, Vol. 12, No. 4BMC Psychiatry, Vol. 17, No. 1Clinical Schizophrenia & Related Psychoses, Vol. 7, No. 4European Neuropsychopharmacology, Vol. 23, No. 8Psychiatry Research, Vol. 187, No. 1-2Early improvement as a predictor of remission and response in schizophrenia: Results from a naturalistic study16 April 2020 | European Psychiatry, Vol. 24, No. 8Schizophrenia Research, Vol. 113, No. 1Schizophrenia Research, Vol. 93, No. 1-3Optimizing Early Prediction for Antipsychotic Response in SchizophreniaJournal of Clinical Psychopharmacology, Vol. 26, No. 6Time Course for Antipsychotic Treatment Response in First-Episode SchizophreniaRobin Emsley, M.D.Jonathan Rabinowitz, Ph.D.Rossella Medori, M.D.1 April 2006 | American Journal of Psychiatry, Vol. 163, No. 4Depression and Anxiety, Vol. 23, No. 8Early Prediction of Antipsychotic Response in SchizophreniaChristoph U. Correll, M.D., Anil K. Malhotra, M.D., Saurabh Kaushik, M.D., Marjorie McMeniman, Ph.D., and John M. Kane, M.D.1 November 2003 | American Journal of Psychiatry, Vol. 160, No. 11Journal of Advanced Nursing, Vol. 30, No. 2Schizophrenia Research, Vol. 30, No. 3La respuesta inicial al fármaco activo y al placebo predice la evolución del tratamiento antidepresivo12 May 2020 | European psychiatry (Ed. Española), Vol. 4, No. 6Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 21, No. 7Initial response to active drug and placebo predicts outcome of antidepressant treatment16 April 2020 | European Psychiatry, Vol. 12, No. 1Die prädiktorische Bedeutung einer Neuroleptika-TestdosisSchizophrenia Research, Vol. 5, No. 2Psychological Medicine, Vol. 21, No. 4Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 14, No. 1Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 14, No. 6Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 13, No. 1-2Acta Psychiatrica Scandinavica, Vol. 72, No. 6Psychiatry Research, Vol. 13, No. 1Comprehensive Psychiatry, Vol. 22, No. 2 Volume 137Issue 9 September 1980Pages 1088-1089 Metrics PDF download History Published online 1 April 2006 Published in print 1 September 1980
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