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Qualitative Profile and Quantitative Determination of Flavonoids from Crocus Sativus L. Petals by LC-MS/MS

2008; SAGE Publishing; Volume: 3; Issue: 12 Linguagem: Inglês

10.1177/1934578x0800301215

1934-578X

Paola Montoro, Carlo Ignazio Giovanni Tuberoso, Mariateresa Maldini, Paolo Cabras, Cosimo Pìzza,

Flavonoids in Medical Research

From the methanolic extract of Crocus sativus petals nine known flavonoids have been isolated and identified, including glycosidic derivatives of quercetin and kaempferol as major compounds (1–2), and their methoxylated and acetylated derivatives. Additionally, LC-ESI-MS qualitative and LC-ESI-MS/MS quantitative studies of the major compounds of the methanolic extract were performed. The high content of glycosylated flavonoids could give value to C. sativus petals, which are a waste product in the production of the spice saffron.