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Graves' Disease Associated with Histologic Hashimoto's Thyroiditis

1985; Wiley; Volume: 93; Issue: 1 Linguagem: Inglês

10.1177/019459988509300117

1097-6817

Stephen A. Falk, Eric A. Birken, A. H. Ronquillo,

Thyroid Cancer Diagnosis and Treatment

The microscopic slides of 16 patients who underwent bilateral subtotal thyroidectomy for hyperthyroid Graves' disease were reviewed and classified into three groups: I, Hashimoto's thyroiditis; II, Graves' disease; and III, both Hashimoto's thyroiditis and Graves' disease. Three patients were classified as group I, 10 as group II, and three as group III. In 38% of the patients with clinical Graves' disease the histologic evidence of Hashimoto's thyroiditis could be found either alone or in combination with histologic evidence of Graves' disease (groups I and III). One patient in group I, four in group II, and three in group III had infiltrative ophthalmopathy (50% of total). Hyperthyroid Graves' disease, Graves' ophthalmopathy, and Hashimoto's thyroiditis can occur all together, in duads, or individually at a specific time in a patient's life.