[Rotavirus diarrhea. Impact in a pediatric hospital of Buenos Aires].
1999; National Institutes of Health; Volume: 59; Issue: 4 Linguagem: Inglês
Autores
Fernanda Gonzalez, Miguel Sordo, G. Rowensztein, L. Sabbag, Anastassios Roussos, Eleonora De Petre, M. Garello, A. Medei, Karin Bok, S Grinstein, Jorge A. Gómez,
Tópico(s)Viral gastroenteritis research and epidemiology
ResumoAnticipating the use of the rotavirus vaccine, we performed this study in order to estimate the rotavirus disease burden in a pediatric hospital. We studied 648 children < 3 years of age between September/97 and August/98, assisted at the Outpatient Diarrhea Unit, or hospitalized due to acute diarrhea in our Hospital. We found rotavirus associated to 36% of the diarrhea cases studied in the Outpatient Clinics, and in 45% of the hospitalized children. We estimate the assistance of 1674 rotavirus diarrheas per year in the Outpatient Clinics, but only 14 of them required hospitalization. The study describes a peak of rotavirus diarrheas between March and June, and another peak of rotavirus-negative diarrheas between January and March (probably due to bacterial diarrheas). Rotavirus disease presented a higher frequency between 6 to 23 months of age; only 10% of the 233 rotavirus cases occurred in children older than 24 months and 13% in infants less than 6 months of age. The situation described is significant because the recently licensed rotavirus vaccine is being used in 3 doses at 2, 4 and 6 months and could have prevented most of the rotavirus cases observed during this study.
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